3
PDGFRA rearrangements
Myeloid or lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions (MLN-TK)
Preface
1
Introduction
2
Work-up for Hypereosinophilia
3
PDGFRA rearrangements
4
FGFR1 rearrangements
5
ETV6 rearrangements
6
Summary
References
3
PDGFRA rearrangements
The majority of MLN-TK cases associated with PDGFRA rearrangements have cytogenetically cryptic deletion of 4q12 resulting in FIP1L1::PDGFRA, but PDGFRA fusions involving other partners are also identified.
2
Work-up for Hypereosinophilia
4
FGFR1 rearrangements